A feed of my publications, literature analyses, and blog posts
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Sak, M. H.; Liu, R. Y.; Kwan, E. E.; Jacobsen, E. N.
Nature 2025, 633, in press. DOI: 10.1038/s41586-025-09813-2
Nature 2025, 633, in press. DOI: 10.1038/s41586-025-09813-2
Accelerating the discovery of multicatalytic cooperativity
publications
Multicat (pooling-deconvolution tool)
blog
Neural network potentials: under the hood (slides)
literature
(Demystifying) Catalytic Deracemization Reactions (slides)
literature
Sak, M. H., Jacobsen, E. N.
Chem. Rev. 2025, XXX, XXX. DOI: 10.1021/acs.chemrev.5c00121
Chem. Rev. 2025, XXX, XXX. DOI: 10.1021/acs.chemrev.5c00121
Selective Noncovalent Catalysis with Small Molecules
publications
A Practical Guide to Operando Low-Temperature NMR Spectroscopy
blog
Solvent effects on Chemical Reactivity and Catalysis (slides)
literature
Lovinger, G. J.,* Sak, M. H.,* Jacobsen, E. N.
Nature 2024, 632, 1052. DOI: 10.1038/s41586-024-07811-4
Nature 2024, 632, 1052. DOI: 10.1038/s41586-024-07811-4
Catalysis of An SN2 Pathway by Geometric Preorganization
publications
The career and legacy of Jay K. Kochi (slides)
literature
Notes from Kochi reading project
literature
Do we vote for papers that end up with more citations?
blog
Enzymatic catalysis: better, but how? (slides)
literature
Paper of the Year 2022
blog
A primer on ML in chemistry (slides)
literature
Eyring calculator (tool)
blog
Turek, A. K., Sak, M. H., Miller, S. J.
J. Am. Chem. Soc. 2021, 143, 16173. DOI: 10.1021/jacs.1c07323
J. Am. Chem. Soc. 2021, 143, 16173. DOI: 10.1021/jacs.1c07323
Kinetic Analysis of a Cysteine-Derived Thiyl-Catalyzed Asymmetric Vinylcyclopropane Cycloaddition Reflects Numerous Attractive Noncovalent Interactions
publications
Chan, Y-C., Sak, M. H., Frank, S. A., Miller, S. J.
Angew. Chem. Int. Ed. 2021, 60, 24573. DOI: 10.1002/anie.202109694
Angew. Chem. Int. Ed. 2021, 60, 24573. DOI: 10.1002/anie.202109694
Tunable and Cooperative Catalysis for Enantioselective Pictet–Spengler Reaction with Varied Nitrogen-Containing Heterocyclic Carboxaldehydes
publications
Coombs, G., Sak, M. H., Miller, S. J.
Angew. Chem. Int. Ed. 2020, 59, 2875. DOI: 10.1002/anie.201913563
Angew. Chem. Int. Ed. 2020, 59, 2875. DOI: 10.1002/anie.201913563
Peptide-Catalyzed Fragment Couplings that Form Axially Chiral Non-C2-Symmetric Biaryls
publications